Characters who are the protagonist's most important, personal, and enduring villain or villains, though most characte... [Read more]
Characters who are the protagonist's most important, personal, and enduring villain or villains, though most characters have only one. Not to be confused with Rival, which features a competitive element, but a character may fulfill both roles. Only applies across long-running series and/or those with many notable villains.
| Name | Series | Gender | Rank | ||
|---|---|---|---|---|---|
| 1 |  | Dio Brando | JoJo's Bizarre Adventure: Phantom Blood | Male | 28 |
| 2 |  | Tomura Shigaraki | Boku no Hero Academia | Male | 409 |
| 3 |  | Loki (Loki Laufeyson) | Marvel | Other | 723 |
| 4 |  | Bowser | Super Mario Bros. | Male | 809 |
| 5 |  | The Joker | DC | Male | 1,087 |
| 6 |  | Dr. Eggman | Sonic the Hedgehog | Male | 1,771 |
| 7 |  | Megatron | Transformers | Male | 2,215 |
| 8 |  | Carnage | Marvel | Other | 2,221 |
| 9 |  | Ganondorf | The Legend of Zelda: Ocarina of Time | Male | 2,891 |
| 10 |  | Dr. Doofenshmirtz | Phineas and Ferb | Male | 3,229 |
| 11 |  | Magneto (Max Eisenhardt) | Marvel | Male | 3,323 |
| 12 |  | Doctor Doom (Victor von Doom) | Marvel | Male | 3,423 |
| 13 |  | Tricky | Madness Combat | Other | 3,764 |
| 14 |  | Eddie Brock | Marvel | Male | 4,546 |
| 15 |  | King Ghidorah | Godzilla | Male | 4,592 |
| 16 |  | Deathstroke (Slade Wilson) | DC | Male | 4,664 |
| 17 |  | Liquid Snake | Metal Gear Solid | Male | 5,549 |
| 18 |  | Lord Voldemort | Harry Potter | Male | 5,684 |
| 19 |  | Doctor Octopus (Otto Octavius) | Marvel | Male | 6,196 |
| 20 |  | Ridley | Metroid | Male | 6,323 |
